Epigenetics Research Kits and Reagents

Epigenetics Research Kits and Reagents

Promega offers kits and reagents for the analysis of DNA methylation, histone modification and RNA transcription to support your epigenetic research.

For methylation evaluation we have methylation activity assays, DNA purification kits, PCR enzymes and master mixes, methylation sensitive restriction enzymes, and basic tools for transfection. We offer Luciferase reporter assays you can use for detection of HDAC, SIRT, methyltransferase and various protease activities. You will also find epigenetics protein purification and interaction kits to analyze histone marks and identify protein binding partners rapidly and efficiently.


 

Cell-Based and Biochemical Assays

We offer luminescent assays you can use for detecting HDAC, SIRT, methyltransferase, Jumonji demethylase and dioxygenase, and various protease activities. The HDAC-Glo™ and SIRT-Glo™ Assays measure the relative activity of histone deacetylase (HDAC) and sirtuins (SIRTs) in a single-reagent-addition, homogeneous assay format. The Succinate-Glo™ Assay can used with any succinate-producing enzyme to rapidly detect demethylase activity in an easy to use add-and-read format.


 

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