Cell Signaling

Promega cell signaling products use the power and convenience of bioluminescence to detect and quantify the activity of various enzymes and proteins involved in signal transduction cascades.

Our biochemical kinase detection platform, ADP-Glo™ Kinase Assay, is a very sensitive and reliable detection method that is easily scaled to meet your throughput needs. Additionally, we offer a large selection of Kinase Enzyme Systems that are optimized for use with ADP-Glo and include over 100 mutants.

The award-winning kinase target engagement assays use NanoBRET® technology to measure kinase-compound binding and residence time in live cells.

Assays are also available for detection of GPCR signaling events, glycosyltransferase activity, and other enzyme activities.

GPCR Signaling Assays

G-protein-coupled receptors (GPCR) represent one of the most important classes of drug targets. We offer a range of easy-to-use, bioluminescence-based GPCR-related assays, ranging from assays that can be used to measure cAMP levels in cells to kits that measure GTPase and PDE activity.

Signaling Pathway Assays

Here you will find assays to detect analytes produced during enzymatic reactions involved in signaling such as ADP, AMP, UDP and GDP as well as growth factors, and phosphatase assays. Kinase assay reagents are found in the Kinase Activity Assays section. Use the filters below to find the product that meets your needs.