Sodium bisulfite, ACS reagent, mixture of NaHSO₃ and Na₂S₂O₅ ยี่ห้อ Sigma

PROPERTIES

grade

ACS reagent

Quality Level

200

form

powder or crystals

concentration

≥58.5% SO₂

impurities

≤0.005% insolubles

pH

4.3 (10 g/L)

anion traces

chloride (Cl^-): ≤0.02%

cation traces

Fe: ≤0.002%

heavy metals (as Pb): ≤0.001%

SMILES string

[Na+].OS([O-])=O

InChI

1S/Na.H2O3S/c;1-4(2)3/h;(H2,1,2,3)/q+1;/p-2

InChI key

DWAQJAXMDSEUJJ-UHFFFAOYSA-L

DESCRIPTION

General description

Sodium bisulfite is a widely used industrial chemical as a reducing agent, catalyst, and preservative in pharmaceuticals and foods due to its antioxidative and antibacterial effects.

The aqueous solutions of sodium bisulfite are acidic in nature. Degradation of sodium bisulfite with acid forms sulfur dioxide gas.[1]

Application

Sodium bisulfite (NaHSO₃) has been used as a reagent to compose the immunoprecipitation (IP) buffer to chemically modify DNA[2] and to synthesize arsenolipids (AsL).[3]

It can also be used as a reagent during the synthesis of 5,6-dihydrouracil-6-sulfonate.[4]

Sodium bisulfite can be used as:

·       A reagent to synthesize aldehyde-bisulfite adducts from aromatic and aliphatic aldehydes.

·       A catalyst in the solvent-free etherification of aromatic/aliphatic alcohols to synthesize symmetric and unsymmetric ethers via intermolecular dehydration.

·       An additive in the copper-catalyzed homocoupling of ketoxime carboxylates to synthesize symmetrical pyrroles.