(R)-Mevalonic acid lithium salt ≥93.0% (qNMR) ยี่ห้อ Sigma

PROPERTIES

Quality Level

100

Assay

≥93.0% (qNMR)

optical activity

[α]/D -26±3°, c = 0.1 in 0.1 M HCl (16 h)

storage temp.

2-8°C

SMILES string

[Li+].C[C@@](O)(CCO)CC([O-])=O

InChI

1S/C6H12O4.Li/c1-6(10,2-3-7)4-5(8)9;/h7,10H,2-4H2,1H3,(H,8,9);/q;+1/p-1/t6-;/m1./s1

InChI key

PVWNXFFXFNEHDZ-FYZOBXCZSA-M

DESCRIPTION

Application

Mevalonic acid may be used as a reference material in assays for the separation or detection of mevalonic acid. Mevalonic acid is a precursor of isopentenyl pyrophosphate (IPP) and the mevalonate pathway which leads to isoprenoid biosynthesis. Mevalonic acid may be used as a substrate to identify and characterize mevalonate kinase(s).

Biochem/physiol Actions

Mevalonic acid[1][2], is an intermediate in the mevalonate pathway, producing terpenes and steroids. This function provides treatment options metabolic disorders[3] [4] [5][6][7][8], R-mevalonate accumulates in patients with the autosomal recessively inherited mevalonic acidurias, an inborn error of cholesterol and nonsterol isoprene biosynthesis[9].

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.