Rabbit anti-Mouse IgG Antibody, HRP Conjugate ยี่ห้อ Sigma-Aldrich

PROPERTIES

biological source

rabbit

Quality Level

100

conjugate

peroxidase conjugate

antibody form

F(ab′)2 fragment of affinity isolated antibody

antibody product type

secondary antibodies

clone

polyclonal

species reactivity

mouse

manufacturer/tradename

Chemicon®

technique(s)

ELISA: suitable

western blot: suitable

shipped in

wet ice

target post-translational modification

unmodified

DESCRIPTION

General description

Immunoglobulin G (IgG) is the most abundant glycoprotein antibody found in human serum. It is secreted by the B cells. IgG structure contains four polypeptide chains, which include two identical heavy (H) chains and two identical λ light (L) chains. These chains are inter-linked by disulfide bonds. IgG exists in four isotypes IgG1, IgG2, IgG3, and IgG4.

Application

Rabbit Anti-Mouse IgG Antibody, HRP conjugate has been used in western blotting. (1:2000)[1](1:200000)[2] (1:5000)[3]

Biochem/physiol Actions

Immunoglobulin G (IgG) aids in the activation of the complement system. It neutralizes virus particles and toxins. IgG facilitates antibody-dependent cell-mediated cytotoxicity (ADCC). Maternal IgG is transferred to the fetus through the placenta that is crucial for protecting newborns against infectious diseases. Detection of IgG levels in severe acute respiratory syndrome coronavirus (SARS‐CoV)‐2 infected patients can be a potential strategy to assess the severity and prognosis of coronavirus disease 2019 (COVID‐19).

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

SAFETY INFORMATION

Storage Class Code

13 - Non Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable