GloResponse(TM) NF-kB-RE-luc2P HEK293 Cell Line ยี่ห้อ Promega (Stroge. Temp BELOW -140C)
รหัสสินค้า : E8520
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GloResponse™ NF-κB-RE-luc2P HEK293 Cell Line
Luciferase Reporter Cell Line with NF-κB Response Element
- Rapid, bioluminescent detection of any cellular response resulting in modulation of NF-κB activities
The GloResponse™ NF-κB-RE-luc2P HEK293 Cell Line is a clonal derivative of Human Embryonic Kidney 293 (HEK293) cells. These cells contain a luciferase gene (luc2P) under the control of a minimal TATA promoter with multiple Nuclear Factor-κB response elements (NF-κB-REs). NF-κB-REs are the DNA-binding sequences for the NF-κB transcription factor, which is responsible for regulating inflammation, immune response, cell growth and apoptosis. The GloResponse™ NF-κB-RE-luc2P HEK293 Cell Line is designed for rapid and convenient analysis of any cellular response that results in modulation of NF-κB activities.
The GloResponse™ Cell Lines incorporate the improvements developed for the pGL4 family of reporter vectors for enhanced performance. The destabilized luc2P luciferase reporter is used for improved responsiveness to transcriptional dynamics. The luc2P gene is codon optimized for enhanced expression in mammalian cells, and the pGL4 plasmid backbone was engineered to reduce background reporter expression. The result is a cell line with very high induction levels when the pathway of interest is activated.
ItemPart #Size
NF-κB-luc2P HEK293 Cell Line
E852A2 × 1 vial
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