Cathepsin s inhibitor screening kit ยี่ห้อ Sigma
รหัสสินค้า : MAK202
| ราคา |
0.00 ฿ |
| จำนวนที่จะซื้อ | |
| ราคารวม | 0.00 ฿ |
PROPERTIES
detection method
fluorometric
storage temp.
−20°C
Gene Information
human ... CTSS(1520)
mouse ... CTSS(13040)
rat ... CTSS(50654)
DESCRIPTION
General description
Cathepsin S (CTSS; EC 3.4.22.27) is a lysosomal cysteine proteinase involved in the degradation of proteins to peptides required for the presentation of MHC class II molecules.1 It is associated with pathological conditions such as atherosclerosis, coronary heart disease, cancer, and insulin resistance.
Suitability
Suitable for the screening of inhibitors of Cathepsin S.
Principle
The Cathepsin S Inhibitor Screening Kit is a simple assay for screening potential inhibitors of CTSS. CTSS activity is measured by cleaving a synthetic 7-amino-4-trifluoromethylcoumarin (AFC)-based substrate to yield AFC, a fluorescent product (λex = 400/ λem = 505 nm), proportional to the enzymatic activity present.
สินค้าไม่เพียงพอ
สินค้าหมด
