Sodium pyruvate powder, BioReagent, suitable for cell culture, suitable for insect cell culture, ≥99% ยี่ห้อ Sigma

PROPERTIES

product line

BioReagent

Quality Level

200

Assay

≥99%

form

powder

technique(s)

cell culture | insect: suitable

cell culture | mammalian: suitable

mp

>300 °C (lit.)

solubility

H2O: 100 mg/mL

storage temp.

2-8°C

SMILES string

[Na+].CC(=O)C([O-])=O

InChI

1S/C3H4O3.Na/c1-2(4)3(5)6;/h1H3,(H,5,6);/q;+1/p-1

InChI key

DAEPDZWVDSPTHF-UHFFFAOYSA-M

DESCRIPTION

General description

Pyruvate is the anion of pyruvic acid.

Application

Sodium pyruvate has been used:

to culture MCF7 ρ0 (human breast cancer cell line) cells as parent cells

as a supplement in extracellular flux (XF) assay media to incubate cells for measuring oxygen consumption rate (OCR)

as a supplement in minimum essential medium Eagle to maintain breast cancer (MCF-7) cells

as a supplement in Dulbecco′s modified Eagle medium (DMEM)-based medium and modified Eagle medium (MEM)-α for testis cell culture to evaluate the effect of medium composition on in vitro SSC maintenance

Biochem/physiol Actions

Sodium Pyruvate has shown antioxidant properties and protective effects against oxygen radicals. Pyruvate is produced as part of glycolysis and is an intermediate in many metabolic pathways. It can be converted into acetyl CoA and enter the TCA Cycle.

Sodium pyruvate can be used as a component in culture broth and media. It exhibits protective effects in various animal models of ischemia-reperfusion injury, hemorrhagic shock, and septic shock when given exogenously.

Features and Benefits

Cell culture and insect cell culture tested