Bioassays
Bioassays
Promega offers an extensive toolbox of reporter bioassays to characterize and develop novel monoclonal antibody (mAb) and cell-based therapeutics.
These assays are useful for interrogating a range of biological functions, including Fc effector activity, immune checkpoint modulation, T cell activation, and cytokine and growth factor signaling.
We maintain a dynamic portfolio of quantitative, accurate and precise bioassays and can partner with drug developers in the early stages of biologic development to ensure that our bioassays meet your needs.
Fc Effector Activity Bioassays
Our ADCC and ADCP Reporter Bioassays are biologically relevant, MOA-based assays that can be used to measure the potency and stability of antibodies and other biologics that specifically bind and activate Fcγ receptors. The assays consist of Jurkat cells stably expressing the relevant Fcγ receptor variant and a luciferase gene regulated by the NFAT response element.
