ViviRen™ Live Cell Substrate

Sensitive Quantitation of Renilla Luminescence in Live Cells

• Engineered coelenterazine for live-cell reporter gene, BRET and RNAi assays
• Permits real-time measurement in multiwell plates
• High signal-to-background ratios

Generate Kinetic Profiles for Reporter Assays, BRET and RNAi in Living Cells

ViviRen™ Live Cell Substrate is a uniquely engineered coelenterazine that generates three- to fivefold brighter Renilla luciferase luminescence than wildtype coelenterazine. Using live cells, achieve up to 100-fold higher signal-to-noise ratios for super-sensitive quantitation of reporter gene, BRET and RNAi activity.

Cat.# E6491 is supplied as a liquid, 60mM in DMSO. Cat.# E6492 and E6495 are supplied as a lyophilized solid.

Assay Advantages

• Quantitate with confidence using miniaturized formats, low-level expression and CCD imagers.
• Unparalleled sensitivity with up to 100-fold higher signal-to-noise ratios than coelenterazine.
• Multiplex with CellTiter-Glo® and other lytic assays for improved accuracy and precision.

ItemPart #Size

ViviRen™ Live Cell Substrate

E649B1 × 3.7mg

แหล่งที่มา : https://worldwide.promega.com/products/luciferase-assays/reporter-assays/viviren-live-cell-substrate/?catNum=E6492