PCR products and DNA from restriction digests are commonly purified away from reaction components to remove any nucleotides or and primers or small molecules that can interfere with performance in downstream applications. The products listed here provide flexible options to purify and concentrate DNA or RNA fragments from PCR and from gels, or to concentrate DNA or RNA from dilute solutions.

The Wizard® SV Gel and PCR Clean-Up System extracts and purifies DNA fragments from agarose gels, or directly from PCR amplification reactions. ReliaPrep™ RNA and DNA Clean-Up and Concentration Systems can be used to concentrate dilute samples in a simple, fast protocol, or to purify DNA or RNA from amplification reactions and gels. The purified/concentrated DNA can be used for sequencing, cloning, labeling, restriction enzyme digestion or in vitro transcription/translation without further manipulation.

The Wizard® MagneSil® Sequencing Reaction Clean-up System provides a convenient magnetic-based method for purification of sequencing reactions that can be easily scaled for high-throughput applications.